• Skip to main content
  • Skip to footer
Gate Science Logo

Gate Science

Gate Science introduces RELAY pain management.

  • About Us
    • Market
    • Executive Team
    • Scientific Advisory Board
  • RELAY
  • News & Events
  • Investors

Developing the first and only SINGLE SOLUTION to control the entire cycle of pain following surgery.

RELAY device

Closing the Gap in the Pain Cycle Following Surgery

After major surgery, pain can persist for weeks; however, currently available non-opioid therapies only address pain for up to 5 days.

Nerve blocks are only effective in controlling pain in the first 8-12 hours after surgery, and nerve blocks with continuous infusion pumps are limited to three to five days of treatment. In recent years, long-acting local analgesic formulations have been developed, but their effect is limited to 72 hours or less. After discharge, opioids remain the cornerstone of pain control for the duration of postoperative recovery.

At Gate Science, our mission is to transform recovery from surgical pain, create a comfortable experience for patients, and eliminate the need for opioids. Our RELAY device is designed to safely control, for the first time, the entire episode of operative pain, including both the severe neuropathic pain of the perioperative period and the prolonged mild to moderate pain in the weeks following surgery… with potential to prevent the progression to chronic pain.

RELAY uniquely combines two established treatment modalities: nerve block, to cover the intense pain immediately following surgery, and neurostimulation, to control the persistent pain in the weeks following discharge. RELAY puts the patient in charge of treatment with the Gate Keeper phone app.

Our technology—and our name—asserts that pain signals emanating from the periphery are controlled with sequential and simultaneous manipulation of two gates in the pathway to the central nervous system.  

The Molecular Gate closes in response to

Nerve Block

The Synaptic Gate closes in response to

Neurostimulation

By combining nerve block and neurostimulation, RELAY interrupts pain signals at both gates, silencing pain without opioids. Gate Science is building a digital platform, Gate Keeper, that initially puts pain management in the hands of the patient and provides entrée to the digital management of pain control in the hours, days, and weeks following surgery. 

“Gate Science’s dual mechanism therapy covering the entire post surgical pain episode has potential to be a real game changer.”

Paul Sethi, MD, President, Orthopedic Surgeon, Orthopedic and Neurosurgery Specialists, PC

For many patients, surgery is the gateway to opioid addiction and its tragic consequences.

Each year, following approximately 50 million surgeries in US, 2.4 million Americans become opioid dependent.

$23.4 Billion of annual healthcare costs associated with addiction can be attributed to postoperative pain.

Without adequate pain control after major procedures, 20-25% of patients progress to chronic persistent pain.

Learn More
About RELAY

Find out how the RELAY device works and how it helps patients, providers, and payers.

Meet the Team
Behind Gate Science

Our executive team has extensive experience and expertise in the field of therapeutic innovation.

The Future of Postoperative
Pain Management

Learn how RELAY’s digital platform, Gate Keeper, puts the patient in control and will incorporate AI to improve outcomes.  

Footer

Gate Science Logo
  • About Us
  • RELAY
  • News & Events
Contact Us

Recent News & Events

  • Gate Science Presentation at LSI USA ’24 in Dana Point, CA April 9, 2024
  • Gate Science Attends NANS 2024 January 15, 2024
  • Webinar: Exploring Tomorrow’s Pain Relief – Innovations, Coverage, and Payment of Non-Opioid Alternatives January 10, 2024

Copyright © 2025 · Gate Science Inc. · Cookie Policy · Privacy Policy